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Lessons learned: Strategies for future pandemic response based on mpox experience – News-Medical.Net

Targeted support for marginalized communities, strong public messaging and a properly coordinated Government approach led by Ministers are amongst the recommendations contained in a new evidence-based article examining how the UK should respond to future pandemics.

Lessons learned: Strategies for future pandemic response based on mpox experience
A new article published by Policy@Manchester examines how the UK can learn the lessons of mpox to respond to future pandemics (Image Credit: iStock.com/whitemay)

Published by The University of Manchester’s policy engagement unit, Policy@Manchester, Dr Maurice Nagington, Dr Jeremy Williams and Dr Jaime Garcia-Iglesias set out key findings from their research on how the country tackled the 2022 outbreak of mpox, formerly known as monkeypox.

Their conclusions were informed by interviews and focus groups with stakeholders including affected communities and healthcare workers.

The academics found “shortcomings in national leadership, stark local and regional inequalities in relation to vaccine access, and inadequate communication infrastructures.”

They offer advice to policymakers and public health officials in four key areas for addressing future infectious disease outbreaks, beginning with reflections on how mpox disproportionately affected marginalized communities.

“People from BAME backgrounds appeared to have lower levels of accessing the vaccine, while those from lower-income populations faced additional barriers to engaging with health and care services,” they observe. “Some individuals also faced challenges in self-isolation such as financial or emotional difficulties.”

They advise: “Public health teams need to be empowered to give additional support (such as financial) where necessary so people can self-isolate.”

The team argue that the needs of marginalized individuals merit equally important consideration when developing effective communications strategies, a second area examined in their article.

“We note social media emerged as a powerful tool in the response to the mpox outbreak, facilitating rapid dissemination of information, promoting awareness, and helping collaboration of a wide range of actors involved in the mpox response,” Nagington, Williams and Garcia-Iglesias write. “The reliance on social media also poses challenges, particularly in terms of equitable access to information.”

In their view, “additional forms of communication that can reach individuals who are marginalized should also be simultaneously developed during outbreaks.” They add: “Community organizations play an important role in developing and distributing information that is suitable and impactful.”

Addressing a third area where they believe action is needed, the academics call for Government agencies – primarily the Department for Health and Social Care – to produce guidance for local public health teams to follow, backed by additional financial support. 

They recommend: “Governments should provide Ministerial level co-ordination to ensure all relevant professionals, policymakers and community representatives work together to proactively address any emerging inequalities in the immediate outbreak and plan for future outbreaks.”

And, with knowledge gained from their research of the “pivotal role” played by sexual health services during the mpox outbreak, Nagington, Williams and Garcia-Iglesias call for policymakers and legislators to “secure adequate funding and support for sexual health services to enhance their capacity to address the demands of outbreaks.”

‘Did the UK fail in its management of mpox? Lessons for future pandemics’ by Dr Maurice Nagington, Dr Jeremy Williams and Dr Jaime Garcia-Iglesias can be read free of charge on the Policy@Manchester website.

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Jesse Plemons Tries to Unpack ‘Kinds of Kindness’ – Hollywood Reporter

Jesse Plemons has become an undisputed auteur’s favorite. The 36-year-old star’s beguiling unshowiness onscreen has landed him memorable parts in films from Paul Thomas Anderson (The Master), Steven Spielberg (Bridge of Spies, The Post), Martin Scorsese (The IrishmanKillers of the Flower Moon), Charlie Kaufman (I’m Thinking of Ending Things), Adam McKay (Vice) and Jane Campion (The Power of the Dog), among so many others. Arguably even more viewers know him from his indelible work on the small screen, which began with his breakthrough role on NBC’s Friday Night Lights, continued through AMC’s landmark hit series Breaking Bad and culminated with an Emmy nomination for FX’s Fargo, where he met his wife, actress and co-star Kirsten Dunst. 

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Plemons touched down for the Cannes Film Festival on Friday for the world premiere of Yorgos Lanthimos’ Kinds of Kindness, the acclaimed Greek director’s follow-up to his multi-Oscar-winning period fantasy Poor Things. Described as a surrealist fable set in the present day, the new project is an anthology film told in three parts, reuniting Lanthimos with the provocative screenwriting partner of his early career, Efthymis Filippou (DogtoothThe LobsterThe Killing of a Sacred Deer). Plemons co-leads an impressive cast including Emma Stone, Willem Dafoe, Margaret Qualley and Hong Chau, with each actor playing three different characters across the film’s thematically interlaced stories. 

The film won raves from critics in Cannes after its Friday night premiere, with The Hollywood Reporter’s lead reviewer David Rooney praising Plemons as “an actor with extraordinary range who’s the standout of a stellar ensemble,” while summing up the movie as “a work of audacious originality, vicious humor and balls-to-the-wall strangeness.”

THR sat down with Plemons at Cannes’ historic Carlton Hotel shortly before Kinds of Kindness’ world premiere. 

What were your impressions when you read the Kinds of Kindness script for the first time? 

Shock. Confusion. By the time I reached the end and finished it, I felt like I had experienced such a wide range of emotions and feelings. My body was just on fire. But then on an intellectual level, you can’t quite comprehend why or what ride you’ve just been on. But that was exciting to me. This isn’t just a weird film for the sake of being weird. There’s something really human about it. I felt that it’s exploring issues that we all deal with but rarely look at in this way. After I read the script a few times — before I really started diving into it in terms of how I was going to play it — it was like I had downloaded all of these feelings, but I had no idea where to put them or how to organize them. So that was strange but exciting. 

What did Yorgos Lanthimos tell you — about his intentions and his ideas for the characters you would be playing? 

He’s not one to explain himself, which is a little unnerving in the beginning. You’re sort of desperate to try and find something to hold on to. And so for me, it was a process of spending a lot of time [with the] script, doing work on my own and making choices, and hoping that they fit into this world. We did talk about certain aspects of it. You know, playing the three different characters. He said early on that he wasn’t into the idea of really extreme transformations and it turning into some actor show-off kind of thing, with everyone showing how different they could be across these three films. So it was about finding this line, where they are different and specific. The physicality was something I was thinking about; the wardrobe really helped. Because, you know, we were wrapping one film, taking the weekend and then starting the next one. So, you make your choices and decide at that point what it means to you — but it constantly changes, because it’s such a movie where, depending on where you are when you watch it or read the script, it totally shifts in how it resonates with you. 

Jesse Plemons, Yorgos Lanthimos and Emma Stone attend the ‘Kinds of Kindness’ photo call in Cannes

Courtesy of Andreas Rentz/Getty Images

The film is set in the contemporary world, but the costumes and the set design feel very specific and slightly heightened in an interesting way. 

Yeah, the colors are very specific, too, right? I really fought for that turtleneck worn by my character Andrew in the first film. Our costume designer really had her work cut out for her — we were basically doing three films at once. And a lot of it was just trial and error — put it on and see how it feels. And with Andrew, we hadn’t looked at anything for him until the camera test. Without thinking, I just put that shirt on and really became attached to it. A lot of it was just a feeling. Yorgos is really collaborative and open, but it has to align with his feeling as well. So it’s an interesting process. 

I want to ask the big, obvious question of how you interpret this movie, but I realize that’s a big ask. 

I know. I’m really conflicted about that question because part of me doesn’t want to give a definitive answer. I don’t think there’s a wrong interpretation. And that’s what is exciting and interesting to me about this movie. Like I said, it changed for me even throughout the course of shooting. Even just looking at one of the three films, I’d be like: “OK, I know what this is now.” And then two days later, I’d think, “No, actually, it’s all of these other things.” Obviously, the themes he’s dealing with in a very general sense are: control, relationships, institutions and things we’re brought up and conditioned just to accept and not to question. These constructs or institutions that are supposed to make us feel safe and secure — or in the case of the religious one, to lead us to some form of transcendence. They’re all, in a nutshell, very simple but very human themes. We’ve just dealt with them in a really roundabout and unusual way. But in my mind, it’s all very universal. 

How about the title? There isn’t a lot of kind behavior in this film. 

Yeah, it’s a pretty messed up title. In a perfect way.

This cast seems like a uniquely cool group of people. Was it a fun set?

Yeah, it was. And it’s not all that common. You know, even though this was my first film with all of them, you stepped onto set and there was this comfortability between everyone. It felt like a weird family theater troupe sort of environment among them. And Willem Dafoe was one of the more interesting creatures I’ve ever met. He just completely marches to the beat of his own drum, and has the excitement and enthusiasm of a 12-year-old theater kid who’s just so happy to be there. 

Trust is always such a big part of what we do — to be willing to take risks. This was such a unique group of crazy-talented people and it felt like everyone had each other’s backs.

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