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Alcohol-related liver disease: Hospitalizations increased among middle-aged women during COVID-19 pandemic – Fortune

Alcohol-related health complications soared among middle-aged women during the early years of the COVID-19 pandemic, according to a new study that calls for heightened attention to alcohol use disorder risk factors in this subset of the U.S. population.

From April 2020 through September 2021, overall hospital visits for alcohol-related conditions spiked beyond what researchers expected, per a study published Friday in the journal JAMA Health Forum. Women ages 40–64, however, saw the largest monthly increases for all conditions, as well as alcohol-related liver disease (ALD) specifically.

Dr. Bryant Shuey, an assistant professor in the Division of General Internal Medicine at the University of Pittsburgh School of Medicine, was lead author of the study. He’s also an internist who treats patients with alcohol use disorder (AUD), and tells Fortune he and his team set out to understand barriers to care for such patients.

“The research builds on the understanding that alcohol use and alcohol-related harms have increased over the last few decades, and that access to effective treatments hasn’t fully been realized,” Shuey says. “We were particularly interested in understanding, were there associations with not just increased alcohol use during the pandemic, but was that associated with alcohol-related harm that we could identify at the emergency department or hospital level.”

Using Optum’s Clinformatics Data Mart database, researchers analyzed the insurance claims data of more than 14.6 million people ages 15 and older, from March 2017 through September 2021. Nearly 30 diagnoses were included, from alcohol abuse with induced psychotic disorder to alcohol dependence with withdrawal delirium. From April 2020 onward, patients in emergency departments, inpatient units, and observation units were diagnosed in these categories:

  • ALD: 57–66%
  • Alcohol withdrawal or alcohol-related mood disorder: 29–37%
  • Alcohol-related cardiomyopathy: 3–4%
  • Alcohol-related gastritis with bleeding: 1–2%

In the overall study population, rates for such conditions increased nearly every month after the pandemic’s onset, but the increases were statistically significant for only four months and ranged from 8–19%. Patients 40–64 showed nine months of statistically significant increases, of 17–36%. Women in this age group had the most pronounced increases: 33–56% across 10 months for all conditions, and 34–95% across 16 months for ALD.

“Alcohol-related liver disease is a very serious condition. It occurs after years—often a decade or more—of persistent, excessive alcohol use,” Shuey explains. “But it can flare and it can worsen acutely, or over the course of weeks to months, with a sudden increase in alcohol use.”

Why is alcohol harm increasing among women?

Skyrocketing alcohol use during the pandemic may have exacerbated ALD among women who already had the condition, Shuey says. It’s just as possible the results of his study reflect newly diagnosed cases, too. Either way, he acknowledges his latest research likely underestimates the number of women with alcohol-related health conditions.

For starters, the stigma surrounding AUD may have led some patients not to disclose their drinking habits with hospital staff. Or, a patient may have been billed under another code not included in the study. In addition, the database includes people who had continuous commercial health insurance or Medicare Advantage coverage for at least six months, leaving out people who were uninsured or underinsured.

“We just hope this study raises the alarm bells even more, and can provide more public health messaging that the gap between men and women in terms of alcohol-related harms is narrowing,” Shuey says.

Women had already begun dying of alcohol-related complications at a higher rate than men in the two decades preceding the pandemic, previous research shows. From 2016 to 2021, deaths from excessive drinking increased by 27% among males and 35% among females, according to the Centers for Disease Control and Prevention. But what are the underlying causes?

“Some people have theorized that this might have to do with normalization of alcohol use in general, as well as targeted marketing toward women with things like wine clubs, seltzers, fun-flavored beverages,” Shuey tells Fortune. “It’s also important to recognize that there’s disproportionate stress on women, who are oftentimes working full-time jobs, taking on a disproportionate share of family responsibilities.”

Even that is speculation, Shuey says: “We simply just don’t know what’s causing this.”

The team’s next step is to explore the pandemic’s effect on access to AUD treatment, namely medication and behavioral therapy. In 2022, less than 10% of adults with the disorder had received any treatment in the last year, according to the National Survey on Drug Use and Health.

If you or a loved one are struggling with alcohol use, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) Alcohol Treatment Navigator can connect you to self-guided programs, telehealth treatment, mutual support groups, and health care professionals who are trained to help. If you need immediate support, contact the 988 Suicide & Crisis Lifeline.

For more on how alcohol impacts your health:

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BREAKING: Gumbo Spills The Beans On Chitepo Assassination | Own Allegation – ZimEye – Zimbabwe News

BREAKING: Gumbo Spills The Beans On Chitepo Assassination | Own Allegation

5 May 2024

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By Political Reporter | Forner ZANU PF Spokesman and Dare ReclChimurenga/Politburo member Rugare Gumbo has dropped his recollection narration of how ZANU PF’s first Chairman, Herbert Chitepo was killed.

Gumbo made this disclosure in clips recorded by …

https://video.twimg.com/amplify_video/1786998906716360704/vid/avc1/1280×720/sdfCTT-_LzLODzdQ.mp4?tag=14

Rugare Gumbo says: Dare ReChimurenga was the supreme Council of when the nationalists movement migrated to Zambia after the disbandment of political parties and Herbert Chitepo was made the director, the chairman of ZANU the external wing. He was the director of prosecutions in Tanzania and then after the UDI in 1965 he took over the external wing and he went to Lusaka so he was based in Lusaka. He started with the revolutionary council which involved the people who were elected in the Congress in 1964- the trained cadres who were outside the country, so they formed a revolutionary Council in 1967 and after 1969 Hebert Chitepo said we have to have an elected body of the party not an appointed body. So they said we have to have a Dare ReChimurenga, of the party; so they held regular conferences to elect new members at bi annual conferences, every two years. So in 1969 they started and elected the new leadership; and then in 1971 they held their second conference, errm in 1973 they held another conference; that is where I come in myself, and I was in America, so that is how I got in, in 1973.

The first Dare ReChimurenga in 1969 involved Chitepo, Hamadziripi, Mukono, Simpson Mutambanengwe, Parirehwa, Mutizwa, and Chitepo?

I had forgotten Shamuyarira in 1971. He was he was the one in charge of foreign affairs. In 1971 Shamuyarira and Mutambanengwe, I think we left them out because there had emerged problems, because Shamuyarira had wanted to take over as chairman of the party and he failed at Kafue Conference of the party.

Then in 1973 there was again an election that’s where I came in; conference at Kafue, that’s why I come in and Chitepo was elected chairman, Cde Mudzi, Cde Hamadziripi, Tongogara came in, myself and Kangai. John Mataure became the political commissar.

I should say in 1971 I had forgotten Richard Hove he had taken over the position that had been under Shamuyarira of foreign affairs, Then Secretary of publicity in 1971 was Washington Malianga.

The function of the Dare ReChimurenga was the overall board that was running the armed struggle and formulated policies, the execution of the armed struggle; basically I would say these are the people who are giving the general direction of the party providing them with the national ideological position to the ministry of defence and also the Recruitment training and welfare of the people who were fighting the cadres and so on and so forth.

You mentioned a particular yeah between 1973 the emerged a breakaway where Froliz came up, what happened there?

Froliz came up in 1971 after the Kafue Conference. What happened was that Shamuyarira wanted to take over as Chairman so that he can work with Chikerema of ZAPU. ZAPU had its own problems of tribalism and so Shamuyarira and Chikerema teamed up and To form the one behind the scenes who were putting Siwela as chairman.

THAT’S WHY IT IS IMPORTANT FOR US IF YOU READ THE TAKE BY MASIPULA, HE TWISTS THAT NARRATIVE TO GIVE CREDIT TO HIS BROTHER, NDABA.

The natives are easily tested so that is why it is important for you the originators to give us the truth .

Ndabaningi Sithole does it feature at all in 1971. Neither does a feature in 1973 he features in after the death of Herbert Chitepo. Before the death of Herbert Chapel when we had a meeting of nationalist in Zambia in December 1974 Sithole was still president of ZANU. A problem had damaged that during that time when they were preparing for that meeting, there was a coup in the prison, at Connemara Prison (in Gweru) where Ndabaningi was ousted by Mugabe; it is reported that Mugabe did not vote but Tekere, and the others the Nkalas, the Maliangas overthrew Sithole in prison.

They had sent Mugabe and Malianga for consultations to do a meeting.

Kaunda wanted Sithole to be president; Sithole and Nkomo, those two were preferred but to Kaunda ‘s surprise there came Mugabe and Malianga.

Kaunda then asked what the heck are you people doing? Who is the president? And they answered saying we later removed him.

How can you remove Sithole the six of you?

Kaunda asked them how on earth can you the six of you do that? Go back. When they had gone back, we then conducted a meeting.

When we held them meeting, we refused and said no there is nothing like that that you remove Sithole when there are just the six of you.

So we decided that we are all united and we then went to the talks while united and we came out within an agreement of Muzorewa, [of Zimbabwe Rhodesia.] LAUGH LAUGH.

The United African Council. So after that, they came some nationalists who when they were now back home problems emerged of the Muzorewa and the Nkomo’s.

Meanwhile, that is when certain people got arrested, on March 4 1975 Sithole was arrested and he was charged with trying to eliminate the other African nationalists, the ANC, these were the tricks of Smith. So After that, that is when that March, on [date unclear] March 18. 1975 is when Hebert Chitepo was assassinated.

So from there that is when the downfall of Sithole began. Sithole was supported by Kaunda who was saying that he thinks that Chitepo was killed by us the Karangas, and Chitepo was Manyika, and yet when Chitepo was killed what actually happened? Was that on the 17th of March 1974 Muzorewa came to Zambia, we went to the airport to welcome him.

We went to sit in our own place just to watch while they were celebrating, the Chikeremas and the Nyandoros. And he arrived and then we went to meet him and then we went to State House to decide on the following day’s meeting on the 18th and when we got there; there were more or less altercations between Nyandoro and Chitepo and so on. Anyway, that is not the issue, but after we agreed to meet tomorrow, we said that Justin Nyoka who was reporting… Isn’t it, you know Justin Nyoka? He said that he wanted to see me and Tongogara so so we then left and went towards Chitepo’s in order to out what our line for the following day tomorrow for about 30 minutes or so to decide who is going to be representing the party externally, the Muzorewa’s were saying this [and that].

So we said Chitepo and Jaison Moyo are those who will represent the party outside the country and so we followed each other and then we had BBC, with the Muzorewa’s and so forth.

Chitepo saw us at the veranda and waved bye-bye we will meet tomorrow. And that was it.

The first time we were in different houses in fear of arrest or so on, but after that we went to one house in a nice way so we can wake up tomorrow to the publicity office to meet Justin Nyoka of the BBC. Tongogara arrived.

As soon as we arrived there, we received a phone call from Mudzi at the liberation centre, he said a bomb has hit at Chitepo’s home. So we said oh.

So right there, Tongogara said to me aah, Gumbo, our liberation struggle has been terminated. Without Chitepo I don’t think our revolution will come out well.

We said that let us go to liberation and as we got to the gate at liberation the commander of SWAPO came and said I am so sorry he is no more political bomb. There has been a bomb at Chitepo’s at Chilenje South. We then went there to see and we saw his body ripped apart. His bodyguard had also been hit and a child and another bodyguard also affected.

So that is how the problems started in ZANU. Even though they had been other problems before, but for the future that is how everything started.

Question: So is it fair to say that the 2017 coup was not the first ZanuPf?

You are quite right. There was another attempt in 1974 to mount a coup against party leadership in Lusaka but basically it was tribal oriented it was of the Manyika’s targeting the Tongogaras.

So it was an attempted coup, but it failed

Question: Were you considered a Karanga as well?

Yes. Myself, Hamadziripi, the Tongogaras.

After that in terms of overthrowal of leadership that I pointed out of Sithole, the first one was done by Mugabe, which failed, and then came this one of 2017.

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Suicide and Other Deaths From Unnatural Causes in Bipolar Disorder – Psychiatric Times

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CONFERENCE REPORTER

A poster at the 2024 American Psychiatric Association (APA) Annual Meeting discussed the results of a recent meta-analysis that investigated the risk of premature mortality, particularly due to unnatural causes like suicide, among individuals with bipolar disorder compared with the general population.

According to the poster’s researchers, there is an association between bipolar disorder and premature mortality. Individuals with bipolar disorder face heightened susceptibility to unnatural deaths, predominantly through suicide, alongside other unnatural causes such as homicide and accidents. The study discussed in the poster undertook a meta-analysis of current research findings concerning these unnatural causes, with a specific focus on suicide in bipolar disorder.1

Following PRISMA guidelines, the study researchers retrieved relevant data from multiple databases including PubMed, Embase, Web of Science, and PsycINFO. A total of 25 studies on suicide and 17 studies on unnatural causes were included in the analysis, which encompassed 180,210 individuals with bipolar disorder for suicide and 349,744 individuals with bipolar disorder for unnatural causes.1

The standardized mortality ratio (SMR) for suicide and unnatural causes was higher in individuals with bipolar disorder compared with the general population. Specifically, the relative risk (RR) for suicide was 11.69, with higher SMR observed in women (17.53) compared with men (14.02). Similarly, the SMR for unnatural causes was 7.29, with higher RR observed in females (9.33) compared with males (6.69). Meta-regression analysis showed no significant influence on results, and publication bias was not observed.1

According to the researchers, the study emphasizes the urgent need for suicide prevention efforts, particularly among individuals with bipolar disorder, as suicide remains a leading cause of preventable death in this population. These findings also underscore the importance of addressing suicide risk factors at both the individual and the population levels through clinical interventions and public health policies.1

“As supported by the data collected, in agreement with previous literature, bipolar disorder subjects presented elevated mortality from unnatural causes—suicide being the most concerning, as it is the leading cause of preventable death,” the researchers concluded. “Our findings lead to an understanding that an effort to prevent suicide is necessary mainly in high-risk bipolar disorder. Clinicians (individual level) and public health policies (populational level) should address risk factors for suicide.”1

The poster was presented by Beny Lafer, MD, PhD, of the University of Toronto Department of Psychiatry, and Taís Biazus, MD, of the University of São Paulo Medical School Department and Institute of Psychiatry.

The suicide rate in the United States recently reached its highest peak since 1941.2 Are you interested in learning more about the latest research on suicide? See the Psychiatric Times® April cover stories on suicide in the context of various comorbidities and patient populations:

A Year of Record-High Suicide Rates

The suicide rate in the United States recently reached its highest peak since 1941. Here’s what you need to know.

Managing Suicidal Thoughts, Behaviors, and Risk in Treatment-Resistant Depression

Which therapeutic targets are likely to be relevant for reducing risk of suicide in TRD?

Preventing Clinician Suicide

Although the practice of medicine can be immensely rewarding, it also can be extraordinarily stressful. Here’s how we can help prevent clinician suicide.

Stay up-to-date on news related to research on promising new interventions and developments in the treatment of a wide variety of psychiatric disorders at psychiatrictimes.com.

Note: This article was prepared with the assistance of ChatGPT.

References

1. Lafer B, Biazus T. Mortality from suicide and unnatural causes among individuals with bipolar disorder: a meta-analysis. American Psychiatric Association Annual Meeting. Poster presentation. May 4, 2024. Accessed May 4, 2024. https://s7.goeshow.com/apa/annual/2024/poster_search.cfm?session_key=010C831E-90B1-1C06-DFD2-E36FA7EFFCFF&session_date=Saturday,%20May%2004,%202024#

2. Kuntz L. A year of record-high suicide rates. Psychiatric Times. April 8, 2024. Accessed May 4, 2024. https://www.psychiatrictimes.com/view/a-year-of-record-high-suicide-rates

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Lecturer/Senior Lecturer/Associate Professor/Professor: Corporate Communications, Photography, Media And Negotiation at Bindura University of Science Education (BUSE) – Pindula Jobs – pindula.co.zw

Job Description

FACULTY OF SOCIAL SCIENCES AND HUMANITIES

Applications are invited from suitably qualified and experienced candidates to fill in the above mentioned position.

The Communication Science Department is the newest addition to the Faculty of Social Sciences and Humanities. It houses the undergraduate Hons Bachelor of Communication Science degree. The Department runs Short Courses in Media and Communication, Media and Digital Marketing, Radio Short Story Writing, Graphics and Desktop Publishing as well as housing the British Council B2B Registration Centre Status for IELTS. Furthermore, the Department also runs a flagship of the University and Faculty: Abiyangu FM Radio Station. If you are successful in the interviews, you can be sure to be joining a growing and dynamic team that could make use of your energy, technical skills as well as innovative ideas.

Duties and Responsibilities

Teach at least three (3) of the following courses:

  • Corporate   Communications, Communication Media and Negotiation Videography and Photography at undergraduate level. Students may be on conventional streams while others may be on block release programmes.
  • The successful candidate should be able to teach some of the Short Courses in Media and Shop-floor Communications. The Department reserves the right   to allocate courses for teaching.
  • Provide academic leadership to the Department/Section, initiate and contribute to basic and applied research in the Department and especially so in respect of Seminars/Workshops that link the university with its communities.
  • Supervise undergraduate students in their fields of specialisation; and
  • Conduct collaborative research within and outside their Department and be involved in University service and community engagement.

NB: Female candidates are encouraged to apply. Police clearance is mandatory for successful candidates.

Qualifications and Experience

  • Applicants must have at least a Master’s degree in Marketing and an Honours degree in Social Sciences (Communication).
  • Focus in dissertation should be in an area that is innovative and demonstrates mastery of frontier knowledge in the area of corporate of communications.
  • Applicants must have a minimum of five (5) years exposure to work environment (Industry) where communication skills were of strategic significance.
  • Must be familiar with the visual art form and technical photography, videography and Desk Top Publishing. Some exposure in collaborative work at institutional level would be an added advantage;
  • Proven record of at least five (5) publications, some ability or willingness to mobilise funding would be a distinct advantage.
  • The curriculum vitae (CV) should contain detailed list of publications; clearly specifying titles of publications, journal names, volumes, page number    details, dates published, name(s) of publishers, name(s) of co-authors if any.
  • Publications should be categorised into books, monographs, refereed and non- refereed journals, chapters in books, etc.

Other

How to Apply

Applications are invited from suitably qualified and experienced candidates to fill in the above mentioned position.

Interested and qualified persons should send one set of their application merged in continuous pdf format to: recruitment@buse.ac.zw consisting of the application letter, certified copies of educational certificates, transcripts, National ID, Birth Certificate and a Curriculum Vitae giving full personal details including full names, place and date of birth, qualifications, previous employment and experience, telephone number, present salary, date of availability, names, e-mail addresses and telephone numbers of at least three referees.

Only shortlisted candidates will be responded to. The closing date for the receipt of applications is Monday, 06 May 2024.

For more information phone: (66210) 7531-2, 7622, 7623, 0772 154 882-9.

“Shaping and Creating the Future: Building Zimbabwe”

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